Dr. Judith Greenberg on Genetics and Developmental Biology


Uploaded by NIGMS on 02.06.2011

Transcript:
Judith Greenberg, Ph.D. Expert in Genetics and Developmental Biology

I’m Judith Greenberg
I’m the Director of the division of genetics and developmental biology at NIGMS.
My division supports research in a wide variety of
areas in genetics and developmental biology
ranging from very mechanistic studies on the regulation
of DNA replication, to gene expression,
studies on cell differentiation and embryonic development, all the way
to studies on evolution and population genetics.
The division, quite simply, has as its mission
to support basic research that lays the foundation for
more disease-related projects that are supported by the
disease-related institutes at NIH.
Most of our grantees use model systems, including yeast, and mice, and worms, and
zebrafish, and flies and many others.
But recently, because of the generation of large amounts of human genomic data,
we’re encouraging more research on –more basic research, on
human –you might say human as a model system for the human, and
examples of this include
Looking at the question of how
variation in gene sequence affects complex genetic traits and genetic diseases.
Another example of using the human as a model is
increasing number of studies on stem cells
where we’re looking at basic questions, such as
how development is regulated.
This division also supports the human genetic cell repository.
This is a repository located at the Coriell Institute for Medical Research in Camden, New Jersey
that supplies well-characterized cell lines and DNA samples from
thousands of individuals either with
genetic disorders, or normal individuals.
And these are used by hundreds of researchers throughout the world
in their studies of cell biology and genetics.
It’s really been quite rewarding over the years as the project officer for this repository
to see the collection evolve And continue to be used for
new purposes, and having really
very, very , important outcomes in understanding human disease.
National Institute of General Medical Sciences National Institutes of Health March 2011