The New Mexico Center for Isotopes in Medicine

Uploaded by unmhsc on 05.02.2010

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JEFFREY NORENBERG: Nuclear pharmacy is similar to other segments of pharmacy. We prepare
patient specific dosage forms. In the case of nuclear pharmacy it’s radiopharmaceuticals
that are used in diagnostic and therapeutic procedures in
nuclear medicine.
JOHN PIEPER: From a research standpoint, our goal is to be one of the premier, pre-clinical
investigation units in nuclear pharmacy in the country. We have always had a very active
research collaboration with our cancer center here
at the University of New Mexico in developing new
products, new diagnostic agents, and played a really vital role in patient care as well.
JOHN PIEPER: When he came here as dean, he realized with Los Alamos being in very close
proximity that it made sense for the College of Pharmacy
to develop the radiopharmacy area of education, research, and most importantly, what, the
innovation that happened here was developing the
business aspect of owning and operating a radiopharmacy.
JEFFREY NORENBERG: So, we’re able to image living systems and to do it in small animals
in ways that very few institutions are able to do. And
so right now our main focus is in drug discovery and
development where we’re identifying unique signatures of disease, mainly in oncology,
and we’re trying to target those unique expressions
of cancer with very specific biomarkers that could be used
either as a diagnostic radiopharmaceutical that would help us diagnose stage and help
us monitor a patient’s response to therapy in a specific
disease state, or they could, uh, be exploited as a target for
some therapeutic intervention, be it a radionuclide, or a toxin, or a drug that could be delivered
with great specificity to these unique signatures
of disease.
JOHN PIEPER: And hopefully we can develop new diagnostic and therapeutic agents that
can then be, after they’re done in a pre-clinical environment,
be taken to patients, with application in our cancer
center. JEFFREY NORENBERG: This is an image of a,
of a mouse that is actually bearing a colorectal tumor
above its left scapula. JOHN PIEPER: So it’s this whole, from Los
Alamos and the isotope to us for drug and formulation and
diagnostic development to animals and then on to patients, and so it’s really creating
this drug development pipeline that goes all the way
from very basic science physics all the way down to
application in people.