Texas A&M Expert Talks About Functions of Natural Products

Uploaded by AggiesTalk on 28.10.2009

Pateamine A is a marine natural product.
A natural product is something that
is isolated from a natural source,
in this case it actually comes from a
marine sponge, and
chemists have actually extracted this
molecule from these sponges and
determined its structure, and then
we, as synthetic chemists, have taken
this compound and explored
its synthesis, explored
its biology.
And this molecule inhibits
protein synthesis, and stops
protein synthesis, which leads to
apoptosis, which is basically
suicide of a cancer cell.
And the idea is that this compound will
selectively kill cancer cells
over normal cells.